![]() ![]() NPS patients carry mutations that result in the loss of a blood circulating factor, a novel hunger hormone called asprosin. Xu’s work published in Nature Medicine in 2017 investigated a rare human disease, neonatal progeroid syndrome (NPS), which is characterized by loss of appetite and extreme leanness. His lab investigates how neurons in the hypothalamus regulate appetite and satiety in mammals, issues associated with current important public health concerns, such as obesity, diabetes and eating disorders.ĭr. Yong Xu is associate professor of pediatrics and of molecular and cellular biology. Area: Pediatrics, Molecular and Human Geneticsĭr. ![]()
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